Epigenetics of Inflammation, Maternal Infection, and Nutrition
نویسندگان
چکیده
منابع مشابه
Epigenetics and Nutrition
Epigenetics refers to the study of heritable changes in gene expression that do not depend on the DNA sequence itself. Those changes alter the phenotype without any change in the genotype and can be influenced by several factors. The environment, the way of living, habits, age, parental nutritional state during gestation and others are amongst the major factors influencing chromatin remodeling....
متن کاملNutrition and Epigenetics
Cardiovascular diseases (CVDs), diabetes, obesity and cancer are polygenic in nature and their prevalences and mortality vary depending upon genetic susceptibility and the presence of phenotype risk factors. The heritability of variant phenotypes may depend on the intake of proinflammatory or anti-inflammatory nutrients, for their expression as phenotypes or their suppression. Genes are importa...
متن کاملNutrition, Epigenetics, and Diseases
Increasing epidemiological evidence suggests that maternal nutrition and environmental exposure early in development play an important role in susceptibility to disease in later life. In addition, these disease outcomes seem to pass through subsequent generations. Epigenetic modifications provide a potential link between the nutrition status during critical periods in development and changes in...
متن کاملNutrition, epigenetics, and metabolic syndrome.
SIGNIFICANCE Epidemiological and animal studies have demonstrated a close link between maternal nutrition and chronic metabolic disease in children and adults. Compelling experimental results also indicate that adverse effects of intrauterine growth restriction on offspring can be carried forward to subsequent generations through covalent modifications of DNA and core histones. RECENT ADVANCE...
متن کاملGastrointestinal Inflammation and Repair: Role of Microbiome, Infection, and Nutrition
Gastrointestinal inflammation is a complex biological response to injury as a result of different stimuli such as pathogens, damaged cells, or irritants. Symbiotic microbiome in digestive tract is considered to protect gut by removing harmful stimuli and to enhance healing process. Alteration or absence of microbiome can lead to exacerbated type 2 immunity and allergic/infectious and inflammato...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2015
ISSN: 0022-3166,1541-6100
DOI: 10.3945/jn.114.194639